Diabetes alters cardiovascular responses to anaesthetic induction agents in STZ-diabetic rats
نویسندگان
چکیده
منابع مشابه
Comparative Effects of Metformin and Glibenclamide on Aortic Reactivity to Vasodilator and Vasoconstrictor Agents in STZ-Induced Diabetic Rats
Background: Diabetes is an important risk factor for cardiovascular events. Endothelial dysfunction is the main reason cause of disability and death in diabetic patients and death. The present study investigates the effects of metformin and glibenclamide on vasoconstrictive and vasodilative responses in the diabetic rat aorta. Methods: Rats were divided into four experimental groups (con...
متن کاملVascular Responses to Anaesthetic Agents* Stewart
ALTHOUGH EFFECTS Of anaesthetic agents on cardiac haemodynamics have been defined 1,'' until recently few data have been available concerning their actions on the peripheral circulation. In this regard, probably the best studied agent is halothane. Among the pertinent observations are decreased hepatic artery resistance in dogs, 3 decreased resistance in the canine hind limb, 4 decreased total ...
متن کاملEffect of melatonin versus vitamin D as antioxidant and Hepatoprotective agents in STZ-induced diabetic rats
BACKGROUND Diabetes mellitus (DM) is a serious chronic disease, with multiple complications including hepatopathy associated with imbalance of the oxidative status. The purpose of this study is to observe possible protective effects of vitamin-D and melatonin on glucose profile, antioxidant-oxidant status, lipid peroxidation, and histopathological protection of the liver in streptozotocin-induc...
متن کاملΔ9-Tetrahydrocannabinol Prevents Cardiovascular Dysfunction in STZ-Diabetic Wistar-Kyoto Rats
The aim of this study was to determine if chronic, low-dose administration of a nonspecific cannabinoid receptor agonist could provide cardioprotective effects in a model of type I diabetes mellitus. Diabetes was induced in eight-week-old male Wistar-Kyoto rats via a single intravenous dose of streptozotocin (65 mg kg-1). Following the induction of diabetes, Δ9-tetrahydrocannabinol was administ...
متن کاملBeneficial role of telmisartan on cardiovascular complications associated with STZ-induced type 2 diabetes in rats.
We studied the effect of an eight-week treatment with telmisartan (5 mg kg(-1)day(-1)) on cardiovascular complications that are associated with type 2 diabetes in a neonatal rat model. Type 2 diabetes was induced by the administration of 90 mg/kg streptozotocin (STZ), ip, in two-day-old rats. The development of diabetes was checked 12 weeks after STZ administration, and the animals were divided...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Diabetes and Vascular Disease Research
سال: 2011
ISSN: 1479-1641,1752-8984
DOI: 10.1177/1479164111421035